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History of Vaccines Blog


Enero 19, 2018  Karie Youngdahl

Influenza activity has been ticking up as the 2017-18 flu season progresses. Twenty pediatric influenza deaths have occurred since the season began in October 2017. The Centers for Disease Control and Prevention’s most recent report for the week ending January 6 shows that 26 states are reporting a high level of influenza-like illness, and 12 states report a moderate level of activity. This influenza season is more severe and active than last season, and it closely resembles the 2014-15 season, which is regarded as a severe season. At this point in that season, 19 pediatric influenza deaths had occurred. For another point of comparison, the proportion of outpatient visits attributed to influenza-like illness (ILI) this week was 5.8%; in the same week of 2014-15, it was 4.4%. The CDC estimates that the 2014-15 season resulted in about 34 million cases of influenza and about 20,000 deaths related directly to influenza. Read more...

Posted in: Influenza, Public Health

Diciembre 5, 2017  Karie Youngdahl

For National Influenza Vaccination Week (NIVW), we interviewed Dalton G. Paxman, PhD, FCPP, Regional Health Administrator for the mid-Atlantic region of U.S. Department of Health and Human Services (HHS). NIVW is a national observance established to highlight the importance of continuing influenza vaccination, as well as fostering greater use of flu vaccine after the holiday season into January and beyond. 1) Why is it important to get an annual flu vaccine Each flu season, the flu virus causes millions of illnesses, hundreds of thousands of hospitalizations and thousands or sometimes tens of thousands of deaths. Getting vaccinated protects you and the people around you, including those who are more vulnerable to serious flu illness, like babies and young children, older people, and people with certain chronic health conditions. 2) Who should get a flu shot? Who shouldn’t? The Centers for Disease Control and Prevention (CDC) recommends annual flu vaccination for everyone 6 months and older, including pregnant women, as long as flu viruses are circulating, which means it’s not too late to get vaccinated, even in January or later. However, there are groups of individuals who should not get the flu vaccine. Those groups include children younger than 6 months old and people with severe, life-threatening allergies to flu vaccine or any of its ingredients. Additionally, people who have an allergy to eggs or other vaccine ingredients, people who have ever had Guillain-Barre Syndrome, and people who are feeling ill should consult with their doctor before getting a flu shot Read more...

Posted in: Influenza, Public Health

Octubre 30, 2017  Karie Youngdahl

On October 18 we conducted our fourth annual influenza vaccination clinic here at The College of Physicians of Philadelphia. By offering the clinic here, during work hours, and for free, we hope to reduce as many barriers to vaccination as possible, such as preventing the trip to the doctor or the pharmacy, overcoming inertia. Of course, we are also hoping to keep staffers, their families and friends, and building visitors healthy, too! We partnered with a service available from our health insurance provider to give the quadrivalent influenza vaccine on site. As an incentive, we gave a $10 Trader Joe's gift card to anyone who got the vaccine. Read more...

Posted in: Influenza

Abril 24, 2017  Karie Youngdahl

By 2017, will polio be eradicated? Will we have a new Lyme disease vaccine? Can we make influenza vaccines more effective? Vaccinologist Stanley A. Plotkin, MD, made a series of predictions for the field for the next ten years that included some hopeful answers to these questions, along with a more pessimistic take on the effect of the current political climate on vaccine acceptance and support for scientific research. Plotkin made his predictions at the National Foundation for Infectious Diseases Annual Conference on Vaccine Research in Bethesda, Maryland. But first, he reviewed his predictions from the 2007 conference when he completed a similar exercise.   Some of his 2007 predictions have come to pass: a new monovalent rotavirus vaccine was licensed, the rotavirus disease burden in developed countries that use the vaccine has been greatly reduced, and the HIV vaccine tested in the Thai trial showed partial efficacy. However, his prediction did not come to pass that by 2017 a prophylactic Type 1 diabetes vaccine for those at high genetic risk of the disease would be licensed. Read more...

Posted in: General, HIV, Influenza, Pertussis (whooping cough), Pneumococcal disease, Polio, Public Health, Rotavirus, Vaccine Research

Febrero 21, 2017  Karie Youngdahl

Are you a glass half empty or glass half full type of person? Your orientation along the optimism-pessimism spectrum will determine whether you think this year’s seasonal influenza vaccine is a moderate success or near failure. The Centers for Disease Control and Prevention released its interim estimate of the 2016-17 influenza vaccine effectiveness (VE) last week: the vaccine appears to be 48% effective at preventing physician-attended influenza illness.This VE estimate is similar to last year’s estimate of 47% VE. You can see a table of VE for 2004-16 here. How does the CDC get these data? CDC used five study sites, where they enrolled patients aged ≥6 months seeking outpatient medical care for an acute respiratory illness (ARI) with cough, within 7 days of illness onset. Researchers interviewed study subjects or their parents to collect respiratory specimens, demographic data, health status, symptoms, and 2016–17 influenza vaccination status. Specimens were tested at U.S. Flu Vaccine Effectiveness Network laboratories using CDC’s real-time reverse transcription – polymerase chain reaction (rRT-PCR) protocol for detection and identification of influenza viruses. Read more...

Posted in: Influenza, Public Health

Diciembre 12, 2015  Karie Youngdahl

For National Influenza Vaccination Week, we welcome Dalton G. Paxman, PhD, MA, FCPP, Regional Health Administrator for the mid-Atlantic region, where he oversees public health initiatives for the Office of the Assistant Secretary for Health (OASH), U.S. Department of Health and Human Services (HHS). Dr. Paxman is a Fellow here at The College of Physicians of Philadelphia.  Read more...

Posted in: Influenza

Octubre 1, 2015  Karie Youngdahl

Yesterday we conducted our second annual influenza vaccination clinic here at The College of Physicians of Philadelphia. By offering the clinic here, during work hours, and for free, we are hoping to reduce as many barriers to vaccination as possible, such as the trip to the doctor or the pharmacy, needing one's insurance card, inertia. Of course we are also hoping to keep staffers, their families and friends, and building visitors healthy, too! We partnered with a local RiteAid pharmacy to give the vaccine, and to provide an incentive, we gave a $10 Trader Joe's gift card to anyone who got the vaccine. The first year I began tracking uptake of influenza vaccine here (2012) only 43% of full-time staff took the vaccine. In 2013, I conducted a brief influenza vaccination awareness campaign and about 70% staffers took the vaccine. Last year, after offering the vaccine here in the building, we were up to 86%, or 38 of 44, vaccinated staffers, including those who’d been vaccinated elsewhere. Read more...

Posted in: Influenza

Diciembre 11, 2014  Karie Youngdahl

For National Influenza Vaccination Week, I had the pleasure of interviewing Dalton G. Paxman, PhD, FCPP, Regional Health Administrator for the mid-Atlantic region, where he oversees public health initiatives for the Office of the Assistant Secretary for Health (OASH), U.S. Department of Health and Human Services (HHS). Dr. Paxman is a Fellow here at The College of Physicians of Philadelphia. Influenza season has begun – has there been much influenza nationally yet? What kind of activity are we seeing in HHS Region 3? Flu activity is beginning to increase in parts of the United States and CDC is getting reports of flu illnesses, flu hospitalizations, and flu deaths. Influenza A (H3N2) viruses are most common so far. H3N2 predominant seasons are associated with more severe illness and mortality, especially in older people and young children, than during H1N1- or B-predominant seasons. If H3N2 viruses continue to predominate, this season could be severe. Read more...

Posted in: Influenza

Diciembre 10, 2014  Karie Youngdahl

It's National Influenza Immunization Week, an observance sponsored every year by the CDC to highlight the national immunization influenza vaccination recommendations. For the past several years, all US individuals in the United States over 6 months of age have been recommended by the Advisory Committee on Immunization Practices to get the influenza vaccine. This influenza season has already been eventful, not only in terms of morbidity and mortality, with five pediatric deaths reported, but also in terms of questions about influenza vaccination effectiveness. First, earlier this fall CDC announced a puzzling finding: in certain groups of children during the 2013-14 flu season, the live attenuated influenza vaccine was less effective against the circulating H1N1 virus than the inactivated vaccine. This finding was unexpected because the live vaccine has in other seasons provided superior protection than the inactivated vaccine.  Read more...

Posted in: Influenza

Octubre 27, 2014  Karie Youngdahl

Here at The College of Physicians of Philadelphia we have about 44 full- and part-time staff people. When a cold or the flu is going around, 10% to 20% of staff can be at home sick. That makes staffing a challenge, particularly because we have to have enough personnel here to sell tickets to the Mütter Museum and staff the museum store. In winter 2013, I polled the employees here and found that only 43% had gotten the flu vaccine in the 2012-13 season. To try to boost our uptake of the vaccine, in fall 2013 I organized a flu vaccine awareness campaign. The result was that about 70% of staffers got the vaccine for the 2013-14 season. This year we decided to reduce all the barriers to vaccination (the trip to the doctor or the pharmacy, needing one's insurance card, inertia), and we brought a pharmacist here to give the trivalent inactivated influenza vaccine to any staffers or contractors who wanted it. As an incentive, and like last year, we gave a $10 Trader Joe's gift card to anyone who got the vaccine. Read more...

Posted in: Influenza