Event Date
2/27/1950
Included in All Dates?
Yes
Unique ID
100317
Associated Media Filename

000365.mov, 000367.mov

Internal Notes

KM: movie file name (000367.mov) conflicts with 000367.jpg, making the jpg image appear as a video still image.

Researcher Hilary Koprowski at Lederle Laboratories conducted the first human trial of his attenuated oral poliovirus vaccine at a New York State facility for intellectually disabled children and children with epilepsy. He tested his Type II vaccine, developed with co-researcher Herald R. Cox (1907-1986), on 20 children and demonstrated that none of them became ill with polio and all of them developed Type II poliovirus antibodies.

At the time, Koprowski’s methods generated considerable controversy among others who were working on experimental vaccines. Many thought that the move to testing a live vaccine in human subjects was premature, and some objected to testing the vaccine on institutionalized children, though the practice was frequent in this era.

Related Media
Diseases & Vaccines
Polio