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Sam Katz, MD, an infectious disease specialist working with Thomas Peebles and other researchers in the Boston lab, tested the first version of the lab’s vaccine on mentally retarded and disabled children at a school outside of Boston. Each of the 11 vaccinated children developed measles antibodies, but nine also developed a mild rash—the vaccine didn’t cause full-blown measles, but it did cause symptoms. The researchers realized the virus used for the vaccine had to be weakened even more.

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