Also BREAKTHROUGHS; NKI note that 358.jpg is a placeholder until LARGE image comes from MOD
In Boston, the team of John Enders, PhD (1897-1985), Thomas Weller, MD (1915-2008), and Frederick Robbins, MD (1916-2003), showed that they could grow polioviruses in non-nervous tissue—namely human embryonic skin and muscle tissue. This landmark finding would reduce reliance on using live monkeys for growing and testing virus. No longer would polio research be restricted to facilities that could house large numbers of experimental animals.
Enders’s findings would lead the way to simpler, less expensive methods of producing large quantities of virus for study and eventually vaccine production.
Enders and colleagues would win the Nobel Prize in Physiology or Medicine in 1954 for their work on culturing polioviruses.
March of Dimes and Polio 4
- The March of Dimes funded the Enders team, which developed a method to grow poliovirus in non-nervous tissue.
March of Dimes archivist David Rose discusses the Foundation's funding of John Enders's work on poliovirus. Until Enders's breakthrough, the only way to grow poliovirus in the laboratory was to use animals. Enders developed a way to grow poliovirus in non-nervous tissue; this work led to a Nobel Prize for him and his team. Their methods reduced the cost of lab work and led to Salk’s vaccine.
- The College of Physicians of Philadelphia
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